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  • Somewhere,
    something incredible is
    waiting to be known.

    Carl Sagan
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CCR Gulbenkian

Cell Cycle Regulation Lab

We study the regulation of cell proliferation with an emphasis on centrioles and cilia. Centrioles are essential for the formation of several microtubule-organizing structures, including centrosomes, cilia, and flagella. Centrosomes are the major microtubule organizer in animal cells, while cilia and flagella are important in signalling and motility. Centriole abnormalities have been observed in a variety of human diseases and understanding the pathways involved in their regulation is invaluable to generate diagnostic and prognostic markers, and provide novel therapeutic targets. We use an integrated approach that combines studies in model organisms and in human cells, with bioinformatics and mathematical modelling.

Latest Publications

  • Louro MAD, Bettencourt-Dias M, Carneiro J. A first-takes-all model of centriole copy number control. PLoS COMPUT BIOL (accepted). more

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What's happening

  • 6 November 2020

    Monica at Cogito Masterclasses

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  • 3 - 6 June 2020

    Sonia Pereira @ EMBO Symposium

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  • April - May 2020

    Joint Volunteering for COVID-19 testing

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  • 02-04 march 2020

    Carla participated in the ASPIC meeting Tumor Microenvironment

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  • 06-07 february 2020

    Another lab retreat of the Cell Cycle Regulation lab

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  • 26 - 29 January 2020

    Marco Louro participated in the Annual Meeting of Gulbenkian phD students in Évora

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