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  • Somewhere,
    something incredible is
    waiting to be known.

    Carl Sagan
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CCR Gulbenkian

Cell Cycle Regulation Lab

We study the regulation of cell proliferation with an emphasis on centrioles and cilia. Centrioles are essential for the formation of several microtubule-organizing structures, including centrosomes, cilia, and flagella. Centrosomes are the major microtubule organizer in animal cells, while cilia and flagella are important in signalling and motility. Centriole abnormalities have been observed in a variety of human diseases and understanding the pathways involved in their regulation is invaluable to generate diagnostic and prognostic markers, and provide novel therapeutic targets. We use an integrated approach that combines studies in model organisms and in human cells, with bioinformatics and mathematical modelling.

Latest Publications

  • Gomes Pereira S, Sousa AL, Nabais C, Paixão T, Holmes AJ, Schorb M, Goshima G, Tranfield EM, Becker JD, Bettencourt-Dias M. The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles. CURRENT BIOLOGY. more

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What's happening

  • 2 - 27 August 2021

    Matilde Palmeira, a summer school student in our lab

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  • 2 - 27 August 2021

    Ana Sofia Faria, a summer school student in our lab

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  • 21 - 24 June 2021

    Monica at the Cell Size and Growth Regulation Meeting

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  • 25 - 28 May 2021

    Mariana at the High Content Image Analysis Workshop

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  • 4 - 6 May 2021

    Pilar at the Neurofly

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  • 23March - 2April 2021

    Pilar and Tânia at the Drosphila Meeting

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