Original Policy Advice And Covid Related Reports:
  1. Almeida P., Amorim MJ, Azevedo L, Carvalho T, Gonçalves de Sá, J, Lobo Antunes J., Perfeito L., Pita Barros P., “Proposta de mapa de controlo pandémico”, 2021. 
  2. Wittwehr, C., Amorim, M. J., Clerbaux, L.-A., Krebs, C., Landesmann, B., Macmillan, D., Nymark, P., Ram, R., Garcia-Reyero, N., Sachana, M., Sullivan, K., Sund, J. and Willett, C. Altex, 2021, “Understanding COVID-19 through adverse outcome pathways – 2nd CIAO AOP Design Workshop”, ATLA 38(2). doi: 10.14573/altex.2102221.
Highlighted in press:
PEERED REVIEWED PUBLICATIONS:

at the igc

  1. Sebastião, C.S.; Cogle, A.; Teixeira, A.D.; Cândido, A.M.; Tchoni, C.; Amorim, M.J.; Loureiro, N.; Parimbelli, P.; Penha-Gonçalves, C.; Demengeot, J.; Sacomboio, E.; Mendes, M.; Arrais, M.; Morais, J.; Vasconcelos, J.N.d.; Brito, M. Clinical Features Related to Severity and Mortality among COVID-19 Patients in a Pre-Vaccine Period in Luanda, Angola. Trop. Med. Infect. Dis. 2022, 7, 338. https://doi.org/10.3390/tropicalmed7110338.
  2. Clerbaux LA, Mayasich SA, Munoz A, Soares H, Petrillo M, Albertini MC, Lanthier N, Grenga L, Amorim MJ. Gut as an alternative entry route for SARS-CoV-2: current evidence and uncertainties of productive enteric infection in COVID-19. 2022, Journal of Clinical Medicine, 11(19). https://doi.org/10.3390/jcm11195691
  3. Jani RA, Cicco AD, Keren-Kaplan T, Vale-Costa S, Hamaoui SD, Hurbain I, Tsai FC, Dimarco M, Macé AS, Zhu Y, Amorim MJ, Bassereau P, Bonifacino JS, Subtil A, Marks MS, Lévy D, Raposo G & Delevoye C. PI4P and BLOC-1 remodel endosomal membranes into tubules. 2022, JCB, https://doi.org/10.1083/jcb.202110132. Also 2021, bioRxiv, 2021.10.21.465321. https://doi.org/10.1101/2021.10.21.465321.
  4. Clerbaux LA, Fillipovska J, Munoz A, Petrillo M, Coecke S, Amorim MJ, Grenga L. Mechanisms leading to gut dysbiosis in COVID-19: current evidence and uncertainties based on putative adverse outcome pathways. 2022, Journal of Clinical Medicine, 2022, 11(18), 5400; https://doi.org/10.3390/jcm11185400
  5. Alenquer M, Milheiro Silva T, Akpogheneta O, Ferreira F, Vale-Costa S, et al. (2022) Saliva molecular testing bypassing RNA extraction is suitable for monitoring and diagnosing SARS-CoV-2 infection in children. PLOS ONE 17(6): e0268388. https://doi.org/10.1371/journal.pone.0268388
  6. Alenquer M, Ferreira F, Lousa D, Valério M, Medina-Lopes M, Bergman M-L, et al. (2021) Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies. PLoS Pathog 17(8): e1009772. https://doi.org/10.1371/journal.ppat.1009772
  7. Goncalves, J.; Julianao, A.M.; Charepe, N.; Alenquer, M.; Athayde, D.; Ferreira, F.; Archer, M.; Amorim, M.J.; Serrano, F.; Soares, H. Non-neutralizing secretory IgA and T cells targeting SARS-CoV-2 spike protein are transferred to the breastmilk upon BNT162b2 vaccination, 2021, medRxiv10.1101/2021.05.03.21256416.  https://doi.org/10.1101/2021.05.03.21256416.
  8. Gabriel, L.; Srinivasan, B.; Kuś, K.; Mata, J.F.; Amorim, M.J.; Jansen, L.E.T.; Athanasiadis, A. Enrichment of Zα domains at cytoplasmic stress granules is due to their innate ability to bind nucleic acids, 2021, J Cell Sci, jcs.258446. https://doi.org/10.1242/jcs.258446
  9. Etibor, T.A.; Yamauchi, Y.; Amorim, M.J. Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives. Viruses, 2021, 13, 366. https://doi.org/10.3390/v13030366
  10. Santos, N.B.; Vaz da Silva, Z.E.; Gomes, C.; Reis, C.A.; Amorim, M.J. Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology, 2021, PLoS Pathog, 17(7):e1009381. https://doi.org/10.1371/journal.ppat.1009381. All raw data available https://doi.org/10.5281/zenodo.4773828. Also in bioRxiv, 10.1101/2021.02.16.431406, https://doi.org/10.1101/2021.02.16.431406.
  11. Gabriel, L.; Srinivasan, B.; Kuś, K.; Mata, J.F.; Amorim, M.J.; Jansen, L.E.T.; Athanasiadis, A. Enrichment of Zα domains at cytoplasmic stress granules is due to their innate ability to bind nucleic acids. bioRxiv, 2021, 10.1101/2021.01.20.427402, 2021.2001.2020.427402, https://doi.org/10.1101/2021.01.20.427402
  12. Ho, J S Y, Angel, M, Ma, Y, Sloan, E, Wang, G, Martinez-Romero, C, Alenquer, M, Roudko, V, Chung, L, Zheng, S, Chang, M, Fstkchyan, Y, Clohisey, S, Dinan, A M, Gibbs, J, Gifford, R, Shen, R, Gu, Q, Irigoyen, N, Campisi, L, Huang, C, Zhao, N, Jones, J D, van Knippenberg, I, Zhu, Z, Moshkina, N, Meyer, L, Noel, J, Peralta, Z, Rezelj, V, Kaake, R, Rosenberg, B, Wang, B, Wei, J, Paessler, S, Wise, H M, Johnson, J, Vannini, A, Amorim, M J, Baillie, J K, Miraldi, E R, Benner, C, Brierley, I, Digard, P, Łuksza, M, Firth, A E, Krogan, N, Greenbaum, B D, MacLeod, M K, van Bakel, H, Garcìa-Sastre, A, Yewdell, J W, Hutchinson, E, Marazzi, I, Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection, 2020, Cell. URL: https://doi.org/10.1016/j.cell.2020.05.035
  13. Alenquer M, Vale-Costa S, Sousa AL, Etibor TA, Ferreira F and Amorim MJ, Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites, 2019, Nature Communications. 10, Article number: 1629 (2019) https://doi.org/10.1038/s41467-019-09549-4 (Research article). See Press Release here​.
  14. Nieto A, Vasilijevic J, Santos NB, et al. Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model. Front Immunol. 2019;10:132. Published 2019 Feb 6. doi:10.3389/fimmu.2019.00132 (Research article).
  15. Amorim MJ. A Comprehensive Review on the Interaction Between the Host GTPase Rab11 and Influenza A Virus. Front Cell Dev Biol. 2019;6:176. Published 2019 Jan 9. doi:10.3389/fcell.2018.00176 
  16. Pereira CF, Wise HM, Kurian D, et al. Effects of mutations in the effector domain of influenza A virus NS1 protein. BMC Res Notes. 2018;11(1):673. Published 2018 Sep 18. doi:10.1186/s13104-018-3779-6 (Research article).
  17. ​Ramos-Nascimento A, Kellen B, Ferreira F, Alenquer M, Vale-Costa S, , Raposo G, Delevoye C and Amorim MJ, “KIF13A mediates influenza A virus ribonucleoproteins trafficking”, Journal of Cell Science, 2017, 130:4038-4050. doi: 10.1242/jcs.210807 (Research article).
  18. Pereira CF, Read EKC, Wise HM, Amorim MJ and Digard P, “The influenza A virus NS1 protein promotes efficient nuclear export of unspliced viral M1 mRNA”, 2017, J. Virology, 91, pii: e00528-17. doi: 10.1128/JVI.00528-17 (Research article).
  19. Sousa AL, Vale-Costa S, Amorim MJ and Tranfield EM, “Using correlative light and electron microscopy to understand influenza A viral assembly", Ultrastructural Pathology, 2017, 41:80. https://doi.org/10.1080/01913123.2016.1269508 (Research article).
  20. Vale-Costa S, Alenquer M, Sousa AL, Kellen B, Ramalho J, Tranfield EM and Amorim MJ, “Influenza A virus ribonucleoproteins modulate host recycling by competing with Rab11 effectors”, Journal of Cell Science, 2016, 129: 1697-1710. https://doi.org/10.1242/jcs.188409 (Research article).
  21. Vale-Costa S and Amorim MJ, “Clustering Rab11 vesicles in influenza A virus infected cells creates hotspots containing the 8 viral ribonucleoproteins”, Small GTPases, 2016, 23: 0-7. https://doi.org/10.1080/21541248.2016.1199190 (Review).
  22. Vale-Costa S and Amorim MJ, “Recycling endosomes and Viral Infection”, Viruses, 2016, 8: 64-92. https://dx.doi.org/10.3390/v8030064 (Review).
  23. Alenquer M, and Amorim MJ, “Exosomes in viral infection: More than ESCRT(ing) viral budding”, Viruses, 2015, 7: 5066-5083. https://dx.doi.org/10.3390/v7092862 (Review).

THE PI BEFORE IGC: 

  1. Amorim MJ, Kao R and Digard P, “Nucleozin targets vRNP-Rab11 complexes circulating in the cytoplasm in influenza A virus infection”, J. Virology, 2013, 87:4694. https://dx.doi.org/10.1128/JVI.03123-12.
  2. Amorim MJ‡, Bruce EA‡, Read EK, Foeglein A, Mahen R, Stuart AD and Digard P, “A Rab11 and microtubule dependent mechanism for transporting influenza A virus vRNA to the plasma membrane via the pericentriolar recycling endosome”, J. Virology, 2011, 85: 4143. https://dx.doi.org/10.1128/JVI.02606-10.
  3. Amorim MJ and Mata, J. “Global coordination of transcriptional control and mRNA decay during cellular differentiation”, Molecular Systems Biology, 2010, 8: 380. https://dx.doi.org/10.1038/msb.2010.38
  4. Amorim MJ and Mata, J, “Rng3p, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally”, EMBO reports, 2009, 10:186-91. https://dx.doi.org/10.1038/embor.2008.228
  5. Amorim MJ, Read EK, Medcalf L and Digard P, “Nuclear export of Influenza A virus mRNAs requires ongoing RNA polymerase II activity”, Traffic, 2007, 8: 1. https://doi.org/10.1111/j.1600-0854.2006.00507.x
  6. Dalton RM, Mullin AE, Amorim MJ, Medcalf L, Tiley L and Digard P, “Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA, complexes”, Virology Journal, 2006, 25: 58. https://dx.doi.org/10.1186/1743-422X-3-58
  7. Amorim MJ and Digard P, “Influenza A virus and the cell nucleus”, Vaccine, 2006, 24: 6651. https://dx.doi.org/10.1016/j.vaccine.2006.05.066    
  8. Elton D, Amorim MJ, Medcalf L and Digard P, “ ‘Genome gating’; polarized intranuclear trafficking of influenza virus RNPs”, Biology Letters, 2004, 1: 113. https://dx.doi.org/10.1098/rsbl.2004.0253. See also Research in Polar Flu Highlight Section in Nature, 2004, 434: 1084. https://dx.doi.org/10.1038/4341084a
  9. Mullin AE, Dalton RM, Amorim MJ, Elton D, Digard P, “Increased amounts of the influenza virus nucleoprotein do not promote higher levels of viral genome replication”, J Gen Virol., 2004, 85:3689. https://dx.doi.org/10.1099/vir.0.80518-0
  10. Carrasco M, Amorim MJ, Digard P, “Lipid raft-dependent targeting of the influenza A virus nucleoprotein to the apical plasma membrane”, Traffic, 2004, 5:979. https://doi.org/10.1111/j.1600-0854.2004.00237.x
  11. Amorim MJ, Ferreira JP, “Microparticles for drug delivering therapeutic peptides and proteins to the lumen of the small intestine”, Eur J Pharm Biopharm, 2001, 52:38. https://dx.doi.org/10.1016/S0939-6411(01)00148-5
  12. Hagen WR, Silva PJ, Amorim MA, Hagedoorn PL, Wassink H, Haaker H, Robb FT, “Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands”, J. Biol Inor Chem, 2000, 5: 527. https://doi.org/10.1007/PL00021452.
SELECTED CONFERENCE COMMUNICATIONS:

at the igc (BY ALL LAB MEMBERS)

Invited seminar on “New paradigms in influenza A virus infection” iMM Monday Lecture series, Lisbon, Portugal, 12thJuly 2021.
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Invited moderator of session “Ciências da Saúde - Doenças Infeciosas e Combate a Agentes Patogénicos” for Portuguese Scientific Meeting 2021, Organized by the FCT, Lisbon, 30th June 2021

Invited speaker, JCR summer school 2021 “Neutralization assays for measuring how SARS-CoV2 variants escape immunity”, Ispra, Italy, 19th May 2021.

Invited speaker “The dialogue between membrane-bound and liquid membraneless organelles during influenza A vírus infection” Institute Curie, 2nd March 2021.

Invited speaker on “The impact of emerging SARS-CoV2 variants in vaccination strategies” webinar on COVID vaccines, 24th February 2021, Fundação Calouste Gulbenkian and La Caixa, virtual meeting.

Invited speaker “How viruses shape the world”, 11th February 2021, International Day of Women and Girls in Science: how ♀ scientists do it! European Commission’s Joint Research Centre, https://pt-semester.eu/events/women-in-science, invited by the EUJRC. https://youtu.be/pfxOCFlij3I

Invited speaker “New paradigms in cell biology”, II symposium in applied biochemistry, 29th January 2021, University of Minho, PT.

Invited seminar “Invited seminar about SARS-CoV-2: Knowns, Unknowns and controversies”, Univerza v Ljubljani, 4thDecember 2020, invited by Emilija Stojmenova Duh.

Invited speaker “How pandemics change lives", Dpt of State of the United States, 28th October 2020

Invited speaker “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Chica and Heinz Schaller foundation Institutional Seminar, 28th January 2020, Heidelberg, Germany.(ATTENDEE:  Amorim M.J.)

Invited speaker “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, EMBO Proteostasis 2019 Meeting, 15th-18th November 2019, Ericeira, PT. (ATTENDEE:  Amorim M.J.)

Invited speaker “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, SPAOM 2019 Meeting, 6th-8th November 2019, Coimbra, PT. (ATTENDEE:  Amorim M.J.)

Speaker: “IMAGING LIQUID ORGANELLES FORMED DURING INFLUENZA INFECTION”, Frontiers in Cellular, Viral and Molecular Microscopy 16th-17th September 2019, Bristol UK. (ATTENDEE:  Amorim M.J.)

Speaker: Marta Alenquer, “Influenza a virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Influenza Update meeting, 17th-18th December 2018, University of Cambridge, UK [Contributed talk]

Speaker-Flash poster session: “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, 'Cell Dynamics: Organelle-Cytoskeleton Interface' Meeting, 19th-22nd May 2019, JCS, Lisbon, PT.(ATTENDEE:  Amorim M.J.)

Speaker: “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Influenza Update meeting, 17th-18th December 2018, University of Cambridge, UK.(ATTENDEE:  Amorim M.J.)

Keynote speaker: “Strategies of influenza A virus adaptation to hosts”, TIBE 2018, international conference, CiBio, 7th-8th December 2018, PT [Invited by TIBE organizing committee, University of Porto, KEYNOTE TALK].(ATTENDEE:  Amorim M.J.)

Speaker, Amorim M.J. “Membrane regulators of complement activation modulate influenza A virus infection”, Munster, 6th International Influenza Meeting, 2-4th September 2018, Munster, Germany.(ATTENDEE:  Amorim M.J.)

Invited speaker: “Mechanisms of influenza A virus modulation of host membrane trafficking”, external seminars, University of Aveiro, 9th May 2018, PT [Invited by Daniela Ribeiro, University of Aveiro, seminar].(ATTENDEE:  Amorim M.J.)

Invited speaker: “Mechanisms of influenza A virus modulation of host membrane trafficking”, Cambridge Virology seminars, University of Cambridge, Dpt of Pathology/Virology, 26th April 2018, Cambridge, UK [Invited by Organiser committee, Division of Virology, University of Cambridge, seminar].(ATTENDEE:  Amorim M.J.)

Invited speaker: “Mechanisms of influenza A virus assembly”, Meeting on Vesicular Biology, 16th-17th February 2018, Coimbra, PT [Invited by Organiser committee, Faculty of Medical Sciences, University of Coimbra, contributed talk].(ATTENDEE:  Amorim M.J.)

Poster: “Membrane regulators of complement activation modulate influenza A virus infection”, Viruses 2018 - Breakthroughs in Viral Replication Conference, 7th-9th February 2018, Barcelona, Spain [Poster].(ATTENDEE:  Amorim M.J.)

Speaker: “Membrane regulators of complement activation modulate influenza A virus infection”, Influenza Update meeting, 21st-22nd November 2017, University of Roslin, Edinburgh, UK.(ATTENDEE:  Amorim M.J.)

Invited speaker: “Mechanisms of influenza A virus assembly”, BioSAM conference FCUL, 22nd April 2017, Lisbon, PT [Invited by Organiser committee, Faculty of Sciences, University of Lisbon, , contributed talk].

Poster: Santos N., Vaz da Silva Z.E. and Amorim M.J. “Influenza A virus-mediated alterations of complement decay-accelerating factor”, EMBO Workshop Proteostasis, Ericeira, Portugal, November 17-21th, 2017 (ATTENDEE: NSantos)

Poster: Vaz-da-Silva ZE and Amorim MJ, Modulation of DAF and CD59 by influenza A viruses, 27th Annual Meeting of the Society for Virology (GFV), Margurg, Germany, March 22-25th, 2017 (ATTENDEE: Zoé E. Vaz-da-Silva).

Talk: Membrane Regulators of Complement Activation impact in influenza A virus pathogenicity, Sociedade Portuguesa de Imunologia, Lisboa, Portugal, June 1-3rd, 2016 (ATTENDEE: Zoé E. Vaz-da-Silva).
                 
Poster: Costa S., Alenquer M., Kellen B and Amorim MJ, “Influenza A virus infection “stalls” sorting of recycling endosomes”, Viruses and cells, Gordon Research Conferences, Barcelona, Spain, Jun 21-26th, 2015 (ATTENDEE: MJAmorim).

Poster: Vaz-da-Silva, EZ and Amorim MJ, “Deficiency in regulators of complement activation - DAF and CD59 -
protects against influenza A virus infection”, Keystone Symposia on Innate Immunity and Determinants of Microbial Pathogenesis, California, USA, April 19-24th, 2015 (ATTENDEE: Zoé E. Vaz-da-Silva)

Poster: Costa S., Alenquer M., Kellen B and Amorim MJ, “Alterations to the recycling endosome during influenza A virus infection”, 33rd American Society of Virology Conference, Colorado, USA, Jun 21-26th, 2014 (ATTENDEE: Silvia Vale-Costa)

Talk: Amorim MJ, Kao R, Digard P., “Influenza A virus replication can be prevented by inhibition of vRNP transport”, 32nd ASV Meeting, Penn State University, USA, July 20-24th, 2013 (ATTENDEE: MJAmorim)

Talk: Amorim MJ, Kao R, Digard P., “Proof of principle for inhibition of vRNP transport in Influenza A virus infection”, 3rd Int. Influenza Meeting, Munster, Germany, 1-3 Sep 2012 (ATTENDEE: MJAmorim)

SELECTED OUTREACH COMMUNICATIONS:

at the igc (BY ALL LAB MEMBERS)

-  July 2019 – Commercial on dynamics and innovation by Journal Observador, sponsored by Seat.

-  May 2019 – Invited for TV programme “consultório” broadcasted by Porto Canal for a 30 minute interview on the importance of fundamental research in virology - http://portocanal.sapo.pt/um_video/QdnHyEHYQZZv0zmdIFLR
​
- May 2019 – Invited for TV news programme “Edição da manhã” by the TV channel SIC.

- April 2019 - Invited for TV news programme “Diário da manhã” by the TV channel TVI, broadcasted simultaneously in TVI24.

- Feb 2019 – Invited as scientist to discuss students perspectives and careers “Jornadas Tecnológicas de Biologia (JORTEC)”, FCT, Universidade Nova, PT.

- May 2018 - Invited seminar on “Vaccination - myths and the science behind it”, for the immunology day organized by the IGC. [Invited by IGC Communication Team, PT].

-  Oct 2017 – Rubric GPS of the programme “Global talk - Falar Global”, CM TV channel. URL: http://www.cmjornal.pt/cmtv/programas/falar-global/detalhe/robos-trabalhadores?ref=falar-global_outras

- Invited lecture on “Yearly epidemics and occasional pandemics”, for the program Schools organized by the IGC, March 2016 (MJAmorim).

- INVITED speaker, ENEB, University of Braga, March 2015 (MJAmorim)

- INVITED speaker, for "Ciència a 4 tempos", Faro, March, 2015

- INVITED TEXT for newspaper entitled "what have viruses taught us about cancer?", June 2015 (MJAmorim)

- Invited speaker, Science Summerschool ANEM 2015, “Motivation to do science (for medical doctors)”, ITQB, July 2015 (MJAmorim).
​
- Invited speaker in Greenfest, Estoril, to discuss “Flu epidemics and pandemics”, Portugal, October 2015 (MJAmorim).

- Organization of the activity on awareness on "Transmission of influenza A virus", IGC Open Day, Oct 2014 (all lab members).

Check Radio interview on this website:
part 1: https://soundcloud.com/ciencia_viva_conversa/maria-joao-amorim-virologista-1-8-abr-2015
part 2: http://www.sulinformacao.pt/2015/04/maria-joao-amorim-virologista-2-15-abril-2015/