Centrioles and cilia are very conserved structures. Our laboratory has been studying cilia and centrosomal structures and their components in different organisms throughout the eukaryotic tree of life (inter-species diversity) to understand how these structures evolved.

We are also very interested in how abnormalities in those structures evolve during disease, in particular in cancer.

Moreover, we are very interested in how diversity of cellular structures originates within an organism (Intra-species diversity), in particular how different centrosome and cilia types originate and can perform highly specialised and different functions.