Susana Montenegro Gouveia

Post-doctoral fellow (Marie Curie fellowship)

I have joined the lab in August 2010. My PhD with Anna Akhmanova (Erasmus Medical Center, The Netherlands) was focused on the microtubule plus ends and on a peculiar group of proteins, the +TIPs. Now, at the CCR, I moved from the plus to the minus end, and will study centrosome biogenesis and centriole elongation.

Publications

Carvalho-Santos Z, Machado P, Alvarez-Martins I, Gouveia SM, Jana SC, Duarte P, Amado T, Branco P, Freitas MC, Silva ST, Antony C, Bandeiras TM, Bettencourt-Dias M. (2012) BLD10/CEP135 is a microtubule-associated protein that controls the formation of the flagellum central microtubule pair. Dev Cell. 23(2):412-24. more

Brito DA, Gouveia SM, Bettencourt-Dias M. (2012) Deconstructing the centriole: structure and number control. Curr Opin Cell Biol. 24(1):4-13. more

van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A. (2011) SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol. 193(6):1083-99. more

Kapitein LC, Yau KW, Gouveia SM, van der Zwan WA, Wulf PS, Keijzer N, Demmers J, Jaworski J, Akhmanova A, Hoogenraad CC. (2011) NMDA receptor activation suppresses microtubule growth and spine entry. J Neurosci. 31(22):8194-209. more

Gouveia SM, Akhmanova A. (2010) Cell and molecular biology of microtubule plus end tracking proteins: end binding proteins and their partners. Int Rev Cell Mol Biol. 285:1-74. more

Montenegro Gouveia S, Leslie K, Kapitein LC, Buey RM, Grigoriev I, Wagenbach M, Smal I, Meijering E, Hoogenraad CC, Wordeman L, Steinmetz MO, Akhmanova A. (2010) In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Curr Biol. 20(19):1717-22. more

Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, Grigoriev I, van Rijssel FJ, Buey RM, Lawera A, Jelesarov I, Winkler FK, Wüthrich K, Akhmanova A, Steinmetz MO. (2009) An EB1-binding motif acts as a microtubule tip localization signal. Cell. 138(2):366-76. more

Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A. (2009) Mammalian end binding proteins control persistent microtubule growth. J Cell Biol. 184(5):691-706. more

Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC. (2009) Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron. 61(1):85-100. more

Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW Jr, Hoogenraad CC, Akhmanova A. (2008) STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol. 18(3):177-82. more