Welcome to our website

About Us

Our Work

Image We study the regulation of cell proliferation with an emphasis on polarity and centrioles. Centrioles are essential for the formation of several microtubule -organizing structures, including centrosomes, cilia and flagella. more

Our Approach

Image An integrated approach combining studies in model organisms with studies in human cells, bioinformatics and mathematical modelling. more

Our Research

Centrosome Biogenesis & Function

ImageCentrioles are essential for the formation of several microtubule (MT) - organizing structures including centrosomes, cilia and flagella. In the centrosome, two centrioles associate with the pericentriolar matrix (PCM), constituting the primary microtubule organizing centre in animal cells. more

Polarity and Cell Cycle Progression

ImageThe loss of epithelial polarity and tissue architecture is a primary diagnostic mark of malignant carcinomas. The relationship between loss of epithelial organization and progression toward malignancy in mammalian tumors has long been known, but whether this is merely correlative or whether loss of architecture might have some causative contribution to tumorigenesis, specifically by affecting cell cycle progression, remains an important question. more

The Team

ImageThere are nine of us in The Cell Cycle Regulation Lab: the PI, five PhD students, one Post-Doc and one research assistant. Each of us works on a different, but complementary project. Currently the group encompasses biologists, biochemists, chemists, cytologists and biological engineers but we welcome people from other backgrounds, such as physics and informatics. more