Welcome to our website
About Us
Our Work
We study the regulation of cell proliferation with an emphasis on centrioles and cilia. Centrioles are essential for the formation of several microtubule-organizing structures, including centrosomes, cilia and flagella. more
Our Approach
Ours is an integrated approach that combines studies in model organisms with studies in human cells, along with bioinformatics and mathematical modelling. more
Our Research
Centrosome Biogenesis & Function
Centrioles are essential for the formation of several microtubule-organizing structures including centrosomes, cilia, and flagella. In the centrosome, two centrioles associate with the pericentriolar matrix, constituting the primary microtubule-organizing centre of animal cells. more
The Team
There are many of us in the Cell Cycle Regulation Lab: the PI, PhD students, Post-Doc fellows, and research assistants. Each of us works on a different, but complementary,
project. Currently, the group encompasses biologists, biochemists, chemists, cytologists, and biological engineers, but we welcome people from other
backgrounds, such as medicine, physics, and informatics (more).
Publications
News
2013-2015 - FCT Post-doctoral Fellowships awarded to Daisuke Ito, Susana Montenegro Gouveia, and Swadhin Jana
2013-2014 - "The Uehara Memorial Foundation" grant (Japan) awarded to Daisuke Ito
Dez2012 - Keith Porter Fellowship awarded to Monica Bettencourt-Dias
Nov2012 - Pfizer Award in Basic Research on the sperm motility study (Dev Cell. 2012 23(2):412-24)
Summer2012 - Laboratory sabbatical in the MBL in Woods Hole in the Summer (7 lab members, loads fun!, see photos)
2012-2014 - FCT Post-doctoral Fellowships awarded to Adán Guerrero, Daniela Brito, and Zita Santos
2011-2015 - European Research Council Starting Grant awarded to our group
2011-2013 - FCT Grant on “Microtubule Regulation in Centriole Biogenesis Mechanisms” awarded to our group
2010-2013 - Harvard-FCT Grant in collaboration with the laboratories of David Pellman (Harvard), Max Loda (Harvard), José Pereira-Leal (IGC), and Paula Chaves (IPO)
2010-2013 - EMBO & Marie Curie Post-doctoral Fellowships awarded to Susana Montenegro Gouveia
New papers from our Group:
- Bettencourt-Dias M. (2013) Q&A: Who needs a centrosome?. BMC Biol. more
- Jana SC, Bazan JF, Bettencourt-Dias M. (2012) Polo boxes come out of the crypt: a new view of PLK function and evolution. Structure more
- Carvalho-Santos Z, Machado P, Alvarez-Martins I, Gouveia SM, Jana SC, Duarte P, Amado T, Branco P, Freitas MC, Silva ST, Antony C, Bandeiras TM, Bettencourt-Dias M. (2012). BLD10/CEP135 is a microtubule-associated protein that controls the formation of the flagellum central microtubule pair. Dev Cell. more
Lab Photos more