Welcome to our website
About Us
Our Work
We study the regulation of cell proliferation with an emphasis on centrioles and cilia. Centrioles are essential for the formation of several microtubule-organizing structures, including centrosomes, cilia and flagella. more
Our Approach
Ours is an integrated approach that combines studies in model organisms with studies in human cells, along with bioinformatics and mathematical modelling. more
Our Research
Centrosome Biogenesis & Function
Centrioles are essential for the formation of several microtubule-organizing structures including centrosomes, cilia, and flagella. In the centrosome, two centrioles associate with the pericentriolar matrix, constituting the primary microtubule-organizing centre of animal cells. more
The Team
There are many of us in the Cell Cycle Regulation Lab: the PI, PhD students, Post-Doc fellows, and research assistants. Each of us works on a different, but complementary,
project. Currently, the group encompasses biologists, biochemists, chemists, cytologists, and biological engineers, but we welcome people from other
backgrounds, such as medicine, physics, and informatics (more).
News
2012-2014 - FCT Post-doctoral Fellowships awarded to Ádan Guerrero, Daniela Brito, and Zita Santos
2011-2015 - European Research Council Starting Grant awarded to our group
2011-2013 - FCT Grant on “Microtubule Regulation in Centriole Biogenesis Mechanisms” awarded to our group
2010-2013 - Harvard-FCT Grant in collaboration with the laboratories of David Pellman (Harvard), Max Loda (Harvard), José Pereira-Leal (IGC), and Paula Chaves (IPO)
2010-2013 - EMBO & Marie Curie Post-doctoral Fellowships awarded to Susana Montenegro Gouveia
New papers from our Group:
- Carvalho-Santos Z, Azimzadeh J, Pereira-Leal JB, Bettencourt-Dias M. Evolution: Tracing the origins of centrioles, cilia, and flagella. (2011) J Cell Biol. J Cell Biol. more
- Bettencourt-Dias M, Hildebrandt F, Pellman D, Woods G, Godinho SA. Centrosomes and cilia in human disease. (2011) Trends Genet. more
- Dzhindzhev NS, Yu QD, Weiskopf K, Tzolovsky G, Cunha-Ferreira I, Riparbelli M, Rodrigues-Martins A, Bettencourt-Dias M, Callaini G, Glover DM. (2010) Asterless is a scaffold for the onset of centriole assembly. Nature. more
Lab Photos more