PEERED REVIEWED PUBLICATIONS:
at the igc
- Ho, J S Y, Angel, M, Ma, Y, Sloan, E, Wang, G, Martinez-Romero, C, Alenquer, M, Roudko, V, Chung, L, Zheng, S, Chang, M, Fstkchyan, Y, Clohisey, S, Dinan, A M, Gibbs, J, Gifford, R, Shen, R, Gu, Q, Irigoyen, N, Campisi, L, Huang, C, Zhao, N, Jones, J D, van Knippenberg, I, Zhu, Z, Moshkina, N, Meyer, L, Noel, J, Peralta, Z, Rezelj, V, Kaake, R, Rosenberg, B, Wang, B, Wei, J, Paessler, S, Wise, H M, Johnson, J, Vannini, A, Amorim, M J, Baillie, J K, Miraldi, E R, Benner, C, Brierley, I, Digard, P, Łuksza, M, Firth, A E, Krogan, N, Greenbaum, B D, MacLeod, M K, van Bakel, H, Garcìa-Sastre, A, Yewdell, J W, Hutchinson, E, Marazzi, I, Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection, 2020, Cell. URL: https://doi.org/10.1016/j.cell.2020.05.035
- Alenquer M, Vale-Costa S, Sousa AL, Etibor TA, Ferreira F and Amorim MJ, Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites, 2019, Nature Communications. 10, Article number: 1629 (2019) https://doi.org/10.1038/s41467-019-09549-4 (Research article). See Press Release here.
- Nieto A, Vasilijevic J, Santos NB, et al. Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model. Front Immunol. 2019;10:132. Published 2019 Feb 6. doi:10.3389/fimmu.2019.00132 (Research article).
- Amorim MJ. A Comprehensive Review on the Interaction Between the Host GTPase Rab11 and Influenza A Virus. Front Cell Dev Biol. 2019;6:176. Published 2019 Jan 9. doi:10.3389/fcell.2018.00176
- Pereira CF, Wise HM, Kurian D, et al. Effects of mutations in the effector domain of influenza A virus NS1 protein. BMC Res Notes. 2018;11(1):673. Published 2018 Sep 18. doi:10.1186/s13104-018-3779-6 (Research article).
- Ramos-Nascimento A, Kellen B, Ferreira F, Alenquer M, Vale-Costa S, , Raposo G, Delevoye C and Amorim MJ, “KIF13A mediates influenza A virus ribonucleoproteins trafficking”, Journal of Cell Science, 2017, 130:4038-4050. doi: 10.1242/jcs.210807 (Research article).
- Pereira CF, Read EKC, Wise HM, Amorim MJ and Digard P, “The influenza A virus NS1 protein promotes efficient nuclear export of unspliced viral M1 mRNA”, 2017, J. Virology, 91, pii: e00528-17. doi: 10.1128/JVI.00528-17 (Research article).
- Sousa AL, Vale-Costa S, Amorim MJ and Tranfield EM, “Using correlative light and electron microscopy to understand influenza A viral assembly", Ultrastructural Pathology, 2017, 41:80. https://doi.org/10.1080/01913123.2016.1269508 (Research article).
- Vale-Costa S, Alenquer M, Sousa AL, Kellen B, Ramalho J, Tranfield EM and Amorim MJ, “Influenza A virus ribonucleoproteins modulate host recycling by competing with Rab11 effectors”, Journal of Cell Science, 2016, 129: 1697-1710. https://doi.org/10.1242/jcs.188409 (Research article).
- Vale-Costa S and Amorim MJ, “Clustering Rab11 vesicles in influenza A virus infected cells creates hotspots containing the 8 viral ribonucleoproteins”, Small GTPases, 2016, 23: 0-7. https://doi.org/10.1080/21541248.2016.1199190 (Review).
- Vale-Costa S and Amorim MJ, “Recycling endosomes and Viral Infection”, Viruses, 2016, 8: 64-92. https://dx.doi.org/10.3390/v8030064 (Review).
- Alenquer M, and Amorim MJ, “Exosomes in viral infection: More than ESCRT(ing) viral budding”, Viruses, 2015, 7: 5066-5083. https://dx.doi.org/10.3390/v7092862 (Review).
THE PI BEFORE IGC:
- Amorim MJ, Kao R and Digard P, “Nucleozin targets vRNP-Rab11 complexes circulating in the cytoplasm in influenza A virus infection”, J. Virology, 2013, 87:4694. https://dx.doi.org/10.1128/JVI.03123-12.
- Amorim MJ‡, Bruce EA‡, Read EK, Foeglein A, Mahen R, Stuart AD and Digard P, “A Rab11 and microtubule dependent mechanism for transporting influenza A virus vRNA to the plasma membrane via the pericentriolar recycling endosome”, J. Virology, 2011, 85: 4143. https://dx.doi.org/10.1128/JVI.02606-10.
- Amorim MJ and Mata, J. “Global coordination of transcriptional control and mRNA decay during cellular differentiation”, Molecular Systems Biology, 2010, 8: 380. https://dx.doi.org/10.1038/msb.2010.38
- Amorim MJ and Mata, J, “Rng3p, a member of the UCS family of myosin co-chaperones, associates with myosin heavy chains cotranslationally”, EMBO reports, 2009, 10:186-91. https://dx.doi.org/10.1038/embor.2008.228
- Amorim MJ, Read EK, Medcalf L and Digard P, “Nuclear export of Influenza A virus mRNAs requires ongoing RNA polymerase II activity”, Traffic, 2007, 8: 1. https://doi.org/10.1111/j.1600-0854.2006.00507.x
- Dalton RM, Mullin AE, Amorim MJ, Medcalf L, Tiley L and Digard P, “Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA, complexes”, Virology Journal, 2006, 25: 58. https://dx.doi.org/10.1186/1743-422X-3-58
- Amorim MJ and Digard P, “Influenza A virus and the cell nucleus”, Vaccine, 2006, 24: 6651. https://dx.doi.org/10.1016/j.vaccine.2006.05.066
- Elton D, Amorim MJ, Medcalf L and Digard P, “ ‘Genome gating’; polarized intranuclear trafficking of influenza virus RNPs”, Biology Letters, 2004, 1: 113. https://dx.doi.org/10.1098/rsbl.2004.0253. See also Research in Polar Flu Highlight Section in Nature, 2004, 434: 1084. https://dx.doi.org/10.1038/4341084a
- Mullin AE, Dalton RM, Amorim MJ, Elton D, Digard P, “Increased amounts of the influenza virus nucleoprotein do not promote higher levels of viral genome replication”, J Gen Virol., 2004, 85:3689. https://dx.doi.org/10.1099/vir.0.80518-0
- Carrasco M, Amorim MJ, Digard P, “Lipid raft-dependent targeting of the influenza A virus nucleoprotein to the apical plasma membrane”, Traffic, 2004, 5:979. https://doi.org/10.1111/j.1600-0854.2004.00237.x
- Amorim MJ, Ferreira JP, “Microparticles for drug delivering therapeutic peptides and proteins to the lumen of the small intestine”, Eur J Pharm Biopharm, 2001, 52:38. https://dx.doi.org/10.1016/S0939-6411(01)00148-5
- Hagen WR, Silva PJ, Amorim MA, Hagedoorn PL, Wassink H, Haaker H, Robb FT, “Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands”, J. Biol Inor Chem, 2000, 5: 527. https://doi.org/10.1007/PL00021452.
SELECTED CONFERENCE COMMUNICATIONS:
at the igc (BY ALL LAB MEMBERS)
INVITED SPEAKER “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Chica and Heinz Schaller foundation Institutional Seminar, 28th January 2020, Heidelberg, Germany.(ATTENDEE: Amorim M.J.)
INVITED SPEAKER “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, EMBO Proteostasis 2019 Meeting, 15th-18th November 2019, Ericeira, PT. (ATTENDEE: Amorim M.J.)
INVITED SPEAKER “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, SPAOM 2019 Meeting, 6th-8th November 2019, Coimbra, PT. (ATTENDEE: Amorim M.J.)
Speaker: “IMAGING LIQUID ORGANELLES FORMED DURING INFLUENZA INFECTION”, Frontiers in Cellular, Viral and Molecular Microscopy 16th-17th September 2019, Bristol UK. (ATTENDEE: Amorim M.J.)
Speaker: Marta Alenquer, “Influenza a virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Influenza Update meeting, 17th-18th December 2018, University of Cambridge, UK [Contributed talk]
Speaker-Flash poster session: “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, 'Cell Dynamics: Organelle-Cytoskeleton Interface' Meeting, 19th-22nd May 2019, JCS, Lisbon, PT.(ATTENDEE: Amorim M.J.)
Speaker: “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Influenza Update meeting, 17th-18th December 2018, University of Cambridge, UK.(ATTENDEE: Amorim M.J.)
Keynote speaker: “Strategies of influenza A virus adaptation to hosts”, TIBE 2018, international conference, CiBio, 7th-8th December 2018, PT [Invited by TIBE organizing committee, University of Porto, KEYNOTE TALK].(ATTENDEE: Amorim M.J.)
Speaker, Amorim M.J. “Membrane regulators of complement activation modulate influenza A virus infection”, Munster, 6th International Influenza Meeting, 2-4th September 2018, Munster, Germany.(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus modulation of host membrane trafficking”, external seminars, University of Aveiro, 9th May 2018, PT [Invited by Daniela Ribeiro, University of Aveiro, seminar].(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus modulation of host membrane trafficking”, Cambridge Virology seminars, University of Cambridge, Dpt of Pathology/Virology, 26th April 2018, Cambridge, UK [Invited by Organiser committee, Division of Virology, University of Cambridge, seminar].(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus assembly”, Meeting on Vesicular Biology, 16th-17th February 2018, Coimbra, PT [Invited by Organiser committee, Faculty of Medical Sciences, University of Coimbra, contributed talk].(ATTENDEE: Amorim M.J.)
Poster: “Membrane regulators of complement activation modulate influenza A virus infection”, Viruses 2018 - Breakthroughs in Viral Replication Conference, 7th-9th February 2018, Barcelona, Spain [Poster].(ATTENDEE: Amorim M.J.)
Speaker: “Membrane regulators of complement activation modulate influenza A virus infection”, Influenza Update meeting, 21st-22nd November 2017, University of Roslin, Edinburgh, UK.(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus assembly”, BioSAM conference FCUL, 22nd April 2017, Lisbon, PT [Invited by Organiser committee, Faculty of Sciences, University of Lisbon, , contributed talk].
Poster: Santos N., Vaz da Silva Z.E. and Amorim M.J. “Influenza A virus-mediated alterations of complement decay-accelerating factor”, EMBO Workshop Proteostasis, Ericeira, Portugal, November 17-21th, 2017 (ATTENDEE: NSantos)
Poster: Vaz-da-Silva ZE and Amorim MJ, Modulation of DAF and CD59 by influenza A viruses, 27th Annual Meeting of the Society for Virology (GFV), Margurg, Germany, March 22-25th, 2017 (ATTENDEE: Zoé E. Vaz-da-Silva).
Talk: Membrane Regulators of Complement Activation impact in influenza A virus pathogenicity, Sociedade Portuguesa de Imunologia, Lisboa, Portugal, June 1-3rd, 2016 (ATTENDEE: Zoé E. Vaz-da-Silva).
Poster: Costa S., Alenquer M., Kellen B and Amorim MJ, “Influenza A virus infection “stalls” sorting of recycling endosomes”, Viruses and cells, Gordon Research Conferences, Barcelona, Spain, Jun 21-26th, 2015 (ATTENDEE: MJAmorim).
Poster: Vaz-da-Silva, EZ and Amorim MJ, “Deficiency in regulators of complement activation - DAF and CD59 -
protects against influenza A virus infection”, Keystone Symposia on Innate Immunity and Determinants of Microbial Pathogenesis, California, USA, April 19-24th, 2015 (ATTENDEE: Zoé E. Vaz-da-Silva)
Poster: Costa S., Alenquer M., Kellen B and Amorim MJ, “Alterations to the recycling endosome during influenza A virus infection”, 33rd American Society of Virology Conference, Colorado, USA, Jun 21-26th, 2014 (ATTENDEE: Silvia Vale-Costa)
Talk: Amorim MJ, Kao R, Digard P., “Influenza A virus replication can be prevented by inhibition of vRNP transport”, 32nd ASV Meeting, Penn State University, USA, July 20-24th, 2013 (ATTENDEE: MJAmorim)
Talk: Amorim MJ, Kao R, Digard P., “Proof of principle for inhibition of vRNP transport in Influenza A virus infection”, 3rd Int. Influenza Meeting, Munster, Germany, 1-3 Sep 2012 (ATTENDEE: MJAmorim)
INVITED SPEAKER “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, EMBO Proteostasis 2019 Meeting, 15th-18th November 2019, Ericeira, PT. (ATTENDEE: Amorim M.J.)
INVITED SPEAKER “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, SPAOM 2019 Meeting, 6th-8th November 2019, Coimbra, PT. (ATTENDEE: Amorim M.J.)
Speaker: “IMAGING LIQUID ORGANELLES FORMED DURING INFLUENZA INFECTION”, Frontiers in Cellular, Viral and Molecular Microscopy 16th-17th September 2019, Bristol UK. (ATTENDEE: Amorim M.J.)
Speaker: Marta Alenquer, “Influenza a virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Influenza Update meeting, 17th-18th December 2018, University of Cambridge, UK [Contributed talk]
Speaker-Flash poster session: “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, 'Cell Dynamics: Organelle-Cytoskeleton Interface' Meeting, 19th-22nd May 2019, JCS, Lisbon, PT.(ATTENDEE: Amorim M.J.)
Speaker: “Influenza A virus ribonucleoproteins form liquid organelles at Endoplasmic reticulum exit sites”, Influenza Update meeting, 17th-18th December 2018, University of Cambridge, UK.(ATTENDEE: Amorim M.J.)
Keynote speaker: “Strategies of influenza A virus adaptation to hosts”, TIBE 2018, international conference, CiBio, 7th-8th December 2018, PT [Invited by TIBE organizing committee, University of Porto, KEYNOTE TALK].(ATTENDEE: Amorim M.J.)
Speaker, Amorim M.J. “Membrane regulators of complement activation modulate influenza A virus infection”, Munster, 6th International Influenza Meeting, 2-4th September 2018, Munster, Germany.(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus modulation of host membrane trafficking”, external seminars, University of Aveiro, 9th May 2018, PT [Invited by Daniela Ribeiro, University of Aveiro, seminar].(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus modulation of host membrane trafficking”, Cambridge Virology seminars, University of Cambridge, Dpt of Pathology/Virology, 26th April 2018, Cambridge, UK [Invited by Organiser committee, Division of Virology, University of Cambridge, seminar].(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus assembly”, Meeting on Vesicular Biology, 16th-17th February 2018, Coimbra, PT [Invited by Organiser committee, Faculty of Medical Sciences, University of Coimbra, contributed talk].(ATTENDEE: Amorim M.J.)
Poster: “Membrane regulators of complement activation modulate influenza A virus infection”, Viruses 2018 - Breakthroughs in Viral Replication Conference, 7th-9th February 2018, Barcelona, Spain [Poster].(ATTENDEE: Amorim M.J.)
Speaker: “Membrane regulators of complement activation modulate influenza A virus infection”, Influenza Update meeting, 21st-22nd November 2017, University of Roslin, Edinburgh, UK.(ATTENDEE: Amorim M.J.)
Invited speaker: “Mechanisms of influenza A virus assembly”, BioSAM conference FCUL, 22nd April 2017, Lisbon, PT [Invited by Organiser committee, Faculty of Sciences, University of Lisbon, , contributed talk].
Poster: Santos N., Vaz da Silva Z.E. and Amorim M.J. “Influenza A virus-mediated alterations of complement decay-accelerating factor”, EMBO Workshop Proteostasis, Ericeira, Portugal, November 17-21th, 2017 (ATTENDEE: NSantos)
Poster: Vaz-da-Silva ZE and Amorim MJ, Modulation of DAF and CD59 by influenza A viruses, 27th Annual Meeting of the Society for Virology (GFV), Margurg, Germany, March 22-25th, 2017 (ATTENDEE: Zoé E. Vaz-da-Silva).
Talk: Membrane Regulators of Complement Activation impact in influenza A virus pathogenicity, Sociedade Portuguesa de Imunologia, Lisboa, Portugal, June 1-3rd, 2016 (ATTENDEE: Zoé E. Vaz-da-Silva).
Poster: Costa S., Alenquer M., Kellen B and Amorim MJ, “Influenza A virus infection “stalls” sorting of recycling endosomes”, Viruses and cells, Gordon Research Conferences, Barcelona, Spain, Jun 21-26th, 2015 (ATTENDEE: MJAmorim).
Poster: Vaz-da-Silva, EZ and Amorim MJ, “Deficiency in regulators of complement activation - DAF and CD59 -
protects against influenza A virus infection”, Keystone Symposia on Innate Immunity and Determinants of Microbial Pathogenesis, California, USA, April 19-24th, 2015 (ATTENDEE: Zoé E. Vaz-da-Silva)
Poster: Costa S., Alenquer M., Kellen B and Amorim MJ, “Alterations to the recycling endosome during influenza A virus infection”, 33rd American Society of Virology Conference, Colorado, USA, Jun 21-26th, 2014 (ATTENDEE: Silvia Vale-Costa)
Talk: Amorim MJ, Kao R, Digard P., “Influenza A virus replication can be prevented by inhibition of vRNP transport”, 32nd ASV Meeting, Penn State University, USA, July 20-24th, 2013 (ATTENDEE: MJAmorim)
Talk: Amorim MJ, Kao R, Digard P., “Proof of principle for inhibition of vRNP transport in Influenza A virus infection”, 3rd Int. Influenza Meeting, Munster, Germany, 1-3 Sep 2012 (ATTENDEE: MJAmorim)
SELECTED OUTREACH COMMUNICATIONS:
at the igc (BY ALL LAB MEMBERS)
- July 2019 – Commercial on dynamics and innovation by Journal Observador, sponsored by Seat.
- May 2019 – Invited for TV programme “consultório” broadcasted by Porto Canal for a 30 minute interview on the importance of fundamental research in virology - http://portocanal.sapo.pt/um_video/QdnHyEHYQZZv0zmdIFLR
- May 2019 – Invited for TV news programme “Edição da manhã” by the TV channel SIC.
- April 2019 - Invited for TV news programme “Diário da manhã” by the TV channel TVI, broadcasted simultaneously in TVI24.
- Feb 2019 – Invited as scientist to discuss students perspectives and careers “Jornadas Tecnológicas de Biologia (JORTEC)”, FCT, Universidade Nova, PT.
- May 2018 - Invited seminar on “Vaccination - myths and the science behind it”, for the immunology day organized by the IGC. [Invited by IGC Communication Team, PT].
- Oct 2017 – Rubric GPS of the programme “Global talk - Falar Global”, CM TV channel. URL: http://www.cmjornal.pt/cmtv/programas/falar-global/detalhe/robos-trabalhadores?ref=falar-global_outras
- Invited lecture on “Yearly epidemics and occasional pandemics”, for the program Schools organized by the IGC, March 2016 (MJAmorim).
- INVITED speaker, ENEB, University of Braga, March 2015 (MJAmorim)
- INVITED speaker, for "Ciència a 4 tempos", Faro, March, 2015
- INVITED TEXT for newspaper entitled "what have viruses taught us about cancer?", June 2015 (MJAmorim)
- Invited speaker, Science Summerschool ANEM 2015, “Motivation to do science (for medical doctors)”, ITQB, July 2015 (MJAmorim).
- Invited speaker in Greenfest, Estoril, to discuss “Flu epidemics and pandemics”, Portugal, October 2015 (MJAmorim).
- Organization of the activity on awareness on "Transmission of influenza A virus", IGC Open Day, Oct 2014 (all lab members).
Check Radio interview on this website:
part 1: https://soundcloud.com/ciencia_viva_conversa/maria-joao-amorim-virologista-1-8-abr-2015
part 2: http://www.sulinformacao.pt/2015/04/maria-joao-amorim-virologista-2-15-abril-2015/
- May 2019 – Invited for TV programme “consultório” broadcasted by Porto Canal for a 30 minute interview on the importance of fundamental research in virology - http://portocanal.sapo.pt/um_video/QdnHyEHYQZZv0zmdIFLR
- May 2019 – Invited for TV news programme “Edição da manhã” by the TV channel SIC.
- April 2019 - Invited for TV news programme “Diário da manhã” by the TV channel TVI, broadcasted simultaneously in TVI24.
- Feb 2019 – Invited as scientist to discuss students perspectives and careers “Jornadas Tecnológicas de Biologia (JORTEC)”, FCT, Universidade Nova, PT.
- May 2018 - Invited seminar on “Vaccination - myths and the science behind it”, for the immunology day organized by the IGC. [Invited by IGC Communication Team, PT].
- Oct 2017 – Rubric GPS of the programme “Global talk - Falar Global”, CM TV channel. URL: http://www.cmjornal.pt/cmtv/programas/falar-global/detalhe/robos-trabalhadores?ref=falar-global_outras
- Invited lecture on “Yearly epidemics and occasional pandemics”, for the program Schools organized by the IGC, March 2016 (MJAmorim).
- INVITED speaker, ENEB, University of Braga, March 2015 (MJAmorim)
- INVITED speaker, for "Ciència a 4 tempos", Faro, March, 2015
- INVITED TEXT for newspaper entitled "what have viruses taught us about cancer?", June 2015 (MJAmorim)
- Invited speaker, Science Summerschool ANEM 2015, “Motivation to do science (for medical doctors)”, ITQB, July 2015 (MJAmorim).
- Invited speaker in Greenfest, Estoril, to discuss “Flu epidemics and pandemics”, Portugal, October 2015 (MJAmorim).
- Organization of the activity on awareness on "Transmission of influenza A virus", IGC Open Day, Oct 2014 (all lab members).
Check Radio interview on this website:
part 1: https://soundcloud.com/ciencia_viva_conversa/maria-joao-amorim-virologista-1-8-abr-2015
part 2: http://www.sulinformacao.pt/2015/04/maria-joao-amorim-virologista-2-15-abril-2015/
